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Determination of nimetazepam and 7-aminonimetazepam in human urine by using liquid chromatography–tandem mass spectrometry

✍ Scribed by Wang, Kuang Chuan (author);Cheng, Min Chi (author);Hsieh, Chin Lin (author);Hsu, Jung Fa (author);Wu, Jen Der (author);Lee, Ching Kuo (author)


Book ID
123544204
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
356 KB
Volume
224
Category
Article
ISSN
0379-0738

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A sensitive and specific high-performance liquid chromatographic/ionspray tandem mass spectrometric (LC/ionspray MS/MS) method was developed and validated to quantitate leukotriene E, (LTE,) in human urine. This method involves solid-phase extraction with Empore membrane disks to isolate LTE, and it