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Determination of neomycin in plasma and urine by high-performance liquid chromatography: Application to a preliminary pharmacokinetic study

✍ Scribed by Badar Shaikh; Jean Jackson; Greg Guyer; William R. Ravis


Book ID
107996848
Publisher
Elsevier Science
Year
1991
Weight
479 KB
Volume
571
Category
Article
ISSN
0378-4347

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## Abstract A simple, specific and sensitive HPLC method with UV detection was developed and validated for the determination of tectoridin in rat plasma for the first time. Chromatographic separation was performed on a Welchrom^TM^ C~18~ column (150 Γ— 4.6Β mm, i.d., 5Β Β΅m) at a flow rate of 1.0Β mLΒ mi