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Determination of natural abundance 15N–1H and 13C–1H dipolar couplings of molecules in a strongly orienting media using two-dimensional inverse experiments

✍ Scribed by H. S. Vinay Deepak; Anu Joy; N. Suryaprakash

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
456 KB
Volume
44
Category
Article
ISSN
0749-1581

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✦ Synopsis

Abstract

NMR spectra of molecules oriented in liquid crystals provide homo‐ and heteronuclear dipolar couplings and thereby the geometry of the molecules. Several inequivalent dilute spins such as ^13^C and ^15^N coupled to protons form different coupled spin systems in their natural abundance and appear as satellites in the proton spectra. Identification of transitions belonging to each spin system is essential to determine heteronuclear dipolar couplings, which is a formidable task. In the present study, using ^15^N^1^H and ^13^C^1^H HSQC, and HMQC experiments we have selectively detected spectra of each rare spin coupled to protons. The ^15^N^1^H and ^13^C^1^H dipolar couplings have been determined in the natural abundance of ^13^C and ^15^N for the molecules pyrazine, pyrimidine and pyridazine oriented in a thermotropic liquid crystal. Copyright © 2006 John Wiley & Sons, Ltd.

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