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Determination of naproxen and its desmethyl metabolite in human plasma or serum by high performance liquid chromatography

✍ Scribed by John T. Slattery; Gerhard Levy

Book ID
108313882
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
286 KB
Volume
12
Category
Article
ISSN
0009-9120

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A simple, rapid, sensitive and selective method for the simultaneous determination of the non-stetoidal anti-inflammatory drug naptoxen (NAP) and its main metabolite the 6-demethylated derivative (DNAP) in human serum is described. The method is based on the intrinsic fluorescence of both acids in a