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Determination of nalmefene in plasma by high-performance liquid chromatography with electrochemical detection and its application in pharmacokinetic studies

✍ Scribed by James Z. Chou; Henrik Albeck; Mary Jeanne Kreek

Publisher
Elsevier Science
Year
1993
Weight
465 KB
Volume
613
Category
Article
ISSN
0378-4347

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## Abstract A simple, specific and sensitive HPLC method with UV detection was developed and validated for the determination of tectoridin in rat plasma for the first time. Chromatographic separation was performed on a Welchrom^TM^ C~18~ column (150 Γ— 4.6Β mm, i.d., 5Β Β΅m) at a flow rate of 1.0Β mLΒ mi