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Determination of Meserine, a new candidate for Alzheimer’s disease in mice brain by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic and tissue distribution study

✍ Scribed by Zheng, Zhaoxi; Tang, Yabin; Lv, Haoyu; Xu, Jianrong; Zhao, Hengyi; Xie, Qiong; Qiu, Zhuibai; Chen, Hongzhuan; Wang, Hao


Book ID
125341991
Publisher
Springer
Year
2014
Tongue
English
Weight
588 KB
Volume
406
Category
Article
ISSN
1618-2650

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## Abstract Zearalenone, a mycotoxin biosynthesized by various __Fusarium__ fungi, is widely found as a contaminant in grains and animal feeds. This study describes a rapid and sensitive LC/MS/MS assay method for the quantification of zearalenone in rat serum. The assay was validated to demonstrate