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Determination of mequitazine in human plasma by gas-chromatography/mass spectrometry with ion-trap detector and its pharmacokinetics after oral administration to volunteers

✍ Scribed by Oh-Seung Kwon; Hye-Jung Kim; Heesoo Pyo; Suk-Jae Chung; Youn Bok Chung


Publisher
Springer
Year
2005
Tongue
English
Weight
761 KB
Volume
28
Category
Article
ISSN
0253-6269

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The determination of biperiden in plasma
✍ B. R. Capacio; S. T. Caro; J. R. Smith; C. E. Byers πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 116 KB πŸ‘ 1 views

## Abstract A gas chromatographic–mass spectrometric (GC‐MS) method has been developed for the analysis of the biperiden from plasma. The method utilizes 290β€…Β΅l of plasma and a simple hexane extraction/clean‐up procedure. Standard curves were linear over the range of 1.9–250β€…ng/mL. The range of cor