Determination of bufuralol and its metab
โ
R. J. Francis; P. B. East; S. J. McLaren; J. Larman
๐
Article
๐
1976
๐
John Wiley and Sons
๐
English
โ 375 KB
๐ 1 views
A sensitive method for the simulataneous determination of bufuralol and its pharmacologically active metabolites in huamn plasma is described. The O-timethylsilyl,N-trifluoroacetyl derivatives are assayed by mass fragmentography. Sensitivity is 1 ng 76(-1) plasma for bufaralol and about 250 pg ml(-1