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Determination of intracellular fludarabine triphosphate in human peripheral blood mononuclear cells by LC–MS/MS

✍ Scribed by Huang, Liusheng; Lizak, Patricia; Aweeka, Francesca; Long-Boyle, Janel

Book ID
122437338
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
381 KB
Volume
86
Category
Article
ISSN
0731-7085

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## Abstract Our previous negative ESI‐LC‐MS/MS method developed for nucleoside reverse transcriptase inhibitor (NRTI) triphosphate (‐TP) measurements in human peripheral blood mononuclear cells (PBMC) encountered some specificity problems for several NRTI‐TP and simultaneous endogenous nucleotide t