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Determination of guanine and its nucleosides and nucleotides in human erythrocytes by high-performance liquid chromatography with postcolumn fluorescence derivatization using phenylglyoxal reagent

โœ Scribed by Sayuri Yonekura; Masatake Iwasaki; Masaaki Kai; Yosuke Ohkura


Publisher
Elsevier Science
Year
1994
Weight
330 KB
Volume
654
Category
Article
ISSN
0378-4347

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Formaldehyde is liberated in the process of cytochrome P450 (CYP) mediated demethylation of a wide variety of compounds containing the CH 3 N or CH 3 O functionality. A highly sensitive method using a highperformance liquid chromatography (HPLC) system with postcolumn derivatization was developed to