The enantiomeric separation of a series of acidic pharmaceuticals (mostly nonsteroidal anti-inflammatory drugs) has been investigated in NACE systems using single-isomer amino beta-CD derivatives. The first part of this study consisted of the selection of the basic experimental conditions to separat
✦ LIBER ✦
Determination of flurbiprofen enantiomers in plasma using a single-isomer amino cyclodextrin derivative in nonaqueous capillary electrophoresis
✍ Scribed by Anne Rousseau; Matteo Pedrini; Patrice Chiap; Robert Ivanyi; Jacques Crommen; Marianne Fillet; Anne-Catherine Servais
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 209 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0173-0835
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The new, single-isomer, octakis 2,3-diacetyl-6-sulfato -␥-cyclodextrin Ž . ODAS-␥ CD has been used for the capillary electrophoretic separation of the enantiomers of weak acids, mostly nonsteroidal anti-inflammatory agents, in a high pH background electrolyte where all the acidic analytes were fully