In principle, equilibrium analytical ultracentrifugation (AU) can be used to quantify the binding stoichiometry and affinity between small-molecule ligands and proteins in aqueous solution. We show here that heteromeric binding constants can be determined using a data-fitting procedure which utilize
โฆ LIBER โฆ
Determination of equilibrium constants and binding capacities using a modified scatchard method in drug-protein binding studies
โ Scribed by Joseph K. H. Ma; H. W. Jun; L. A. Luzzi
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- English
- Weight
- 285 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0022-3549
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