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Determination of doxycycline in small serum samples by liquid chromatography. Application to pharmacokinetical studies on small laboratory animals

✍ Scribed by I. Gastearena; M. C. Dios-Viéitez; E. Segura; M. M. Goñi; M. J. Renedo; D. Fos

Book ID
112721288
Publisher
Springer
Year
1993
Tongue
English
Weight
178 KB
Volume
35
Category
Article
ISSN
0009-5893

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## Abstract A simple, specific and sensitive HPLC method with UV detection was developed and validated for the determination of tectoridin in rat plasma for the first time. Chromatographic separation was performed on a Welchrom^TM^ C~18~ column (150 × 4.6 mm, i.d., 5 µm) at a flow rate of 1.0 mL mi