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Determination of dichloroacetic acid in plasma and urine

โœ Scribed by Heizmann, P. ;Von Alten, R.


Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
116 KB
Volume
2
Category
Article
ISSN
0935-6304

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โœฆ Synopsis


Abstract

A method for the measurement of dichloroacetic acid in plasma or urine has been developed. The method involves extraction of dichloroacetic acid into diethyl ether, evaporation of the etheric phase to a small volume and derivatization with diazomethane. Trichloroacetic acid was used as an internal standard. Concentrations as low as 50 ng/ml can be determined.


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