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Determination of Corosolic Acid, a Natural Potential Anti-Diabetes Compound, in Rat Plasma by High-Performance Liquid Chromatography-Mass Spectrometry and its Application to Pharmacokinetic and Bioavailability Studies

✍ Scribed by Liu, Qingwang; Zhao, Di; Chen, Xijing; Li, Zhubo; Li, Ning; Han, Deen; Talbi, Amer; Biwoele, Tarcisse

Book ID
125852378
Publisher
Thieme Medical Publishers
Year
2011
Tongue
German
Weight
123 KB
Volume
77
Category
Article
ISSN
0032-0943

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## Abstract A simple, specific and sensitive HPLC method with UV detection was developed and validated for the determination of tectoridin in rat plasma for the first time. Chromatographic separation was performed on a Welchrom^TM^ C~18~ column (150 Γ— 4.6Β mm, i.d., 5Β Β΅m) at a flow rate of 1.0Β mLΒ mi