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Determination of codeine and metabolites in plasma and urine using ion-pair high-performance liquid chromatography

✍ Scribed by J.O. Svensson; Q.Y. Yue; J. Säwe


Publisher
Elsevier Science
Year
1995
Weight
336 KB
Volume
674
Category
Article
ISSN
0378-4347

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A procedure is described for the simultaneous determination of codeine and ibuprofen in human plasma following the administration of the two substances in a proposed combination dosage form. The two substances were extracted separately from plasma and then determined together by high-performance liq