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Determination of theophylline and its metabolites in human urine and plasma by high-performance liquid chromatography

✍ Scribed by Birgitte Buur Rasmussen; Kim Brøsen


Publisher
Elsevier Science
Year
1996
Weight
355 KB
Volume
676
Category
Article
ISSN
0378-4347

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Determination of Theophylline Metabolite
✍ B.B. Rasmussen; K.K. Nielsen; K. Brosen 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 347 KB

A method for the quantitation of three metabolites of theophylline, 1-methylxanthine (1MX), 3-methylxanthine (3MX), and 1,3 -dimethyluric acid (13DMU) in human liver microsomes has been developed. The method is based on a simple one-step extraction followed by isocratic, reversed-phase high-performa