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Determination of carbamazepine and carbamazepine 10,11-epoxide in human plasma by tandem liquid chromatography–mass spectrometry with electrospray ionisation

✍ Scribed by G.F van Rooyen; D Badenhorst; K.J Swart; H.K.L Hundt; T Scanes; A.F Hundt


Book ID
108497243
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
119 KB
Volume
769
Category
Article
ISSN
1873-376X

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Simultaneous determination by gas-liquid
✍ Robin E. Chambers 📂 Article 📅 1978 🏛 Elsevier Science 🌐 English ⚖ 196 KB

Carbamazepine-lO,l l-epoxide is a metabolite of carbamazepine that has been identified in the urine OT the rat and in the urine and plasma of marV and which, in the rat, has been shown to have antiepileptic properties comparable to those of the parent drug. It has therefore been suggested3 that, in