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Determination of amines as pentafluoropropionic acid anhydride derivatives in biological samples using liquid chromatography and tandem mass spectrometry

✍ Scribed by Marand, �sa; Karlsson, Daniel; Dalene, Marianne; Skarping, Gunnar

Book ID
121681713
Publisher
Royal Society of Chemistry
Year
2004
Tongue
English
Weight
114 KB
Volume
129
Category
Article
ISSN
0003-2654

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## Abstract Sphingosine kinase (SphK) is a key enzyme in modulating the levels of sphingosine 1‐phosphate (S1P) as well as an important enzyme in numerous biological responses. Using C17‐sphingosine as a substrate, we established a rapid, sensitive and highly efficient method for determination of S