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Determination of adducts between styrene oxide and N-7 guanine with acetylation method

✍ Scribed by Savela, K.; Hesso, A.; Hemminki, K.


Book ID
121892793
Publisher
Elsevier Science
Year
1987
Weight
123 KB
Volume
23
Category
Article
ISSN
0277-5379

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✍ Jan Novák; Igor Linhart; Hana Dvorˇáková 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 222 KB 👁 1 views

## Abstract 7‐(2‐Hydroxy‐1‐phenylethyl)‐ and 7‐(2‐hydroxy‐2‐phenylethyl)guanines are important DNA adducts which can be used as markers of exposure to styrene. Two synthetic routes leading to these compounds are presented using allyl‐protected bromohydrins as synthetic equivalents of styrene oxide