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Determination of (22R,S)budesonide in human plasma by automated liquid chromatography/thermospray mass spectrometry

✍ Scribed by Claes Lindberg; Ann Blomqvist; Jan Paulson


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
651 KB
Volume
21
Category
Article
ISSN
1076-5174

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A sensitive and selective method was developed for the determination of (R)-ketoprofen ((R)-kt) and (S )-ketoprofen ((S )-kt) in human plasma using chiral liquid chromatography/tandem mass spectrometry (LC/MS/MS). Plasma samples spiked with stable-isotope-labeled [ 13 C 1 , 2 H 3 ]-(R and S )-ketopr