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Determinants of water proton T1 in blood serum

✍ Scribed by H. H. Raeymaekers; D. Borghys; H. Eisendrath


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
247 KB
Volume
6
Category
Article
ISSN
0740-3194

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✦ Synopsis


Water proton TI (10.7 MHz; 7Β°C) and albumin and globulin contents were measured in the blood serum of 30 normal volunteers. The T I relaxivity of serum albumin and globulin (i.e., the change of water relaxation rate l/TI per concentration unit) was determined in pure albumin and globulin solutions. It is shown that more than 90% of the serum relaxation rate I/Tl is due to the proteins, making TI a nonspecific blood parameter. In addition five pathologkal serum samples were examined, explaining clearly why serum T, is not a clinically useful measurement. o 1988 Academic press, Inc.


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