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Determinants of clearance of tissue-type plasminogen activator (t-PA) from the circulation

✍ Scribed by Devries, S.R.; Fox, K.A.A.; Robison, A.; Rodriguez, R.U.; Sobel, B.E.


Book ID
123282185
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
607 KB
Volume
1
Category
Article
ISSN
0268-9499

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Full-length tissue-type plasminogen activator (t-PA) cDNA served to construct deletion mutants within the N-terminal "heavy" (H)-chain of the t-PA molecule. The H-chain cDNA consists of an array of structural domains homologous to domains present on other plasma proteins ("finger, " "epidermal growt