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Determinants of acetaminophen metabolism: Effect of inducers and inhibitors of drug metabolism on acetaminophen's metabolic pathways

✍ Scribed by Miners, John O; Attwood, Janet; Birkett, Donald J

Book ID
109843564
Publisher
Nature Publishing Group
Year
1984
Tongue
English
Weight
557 KB
Volume
35
Category
Article
ISSN
0009-9236

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The effect of salicylamide and acetaminophen on the metabolic fate of dextrorphan, the primary metabolite of dextromethorphan, was studied in vivo in the rat. Plasma dextrorphan levels were measured at 5-min intervals up to 20 min and at longer intervals up to 2 hr after dextromethorphan hydrobromid