Osteoclastic superoxide production and b
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Alix G. Darden; William L. Ries; William C. Wolf; Ramona Marie Rodriguiz; L. Lyn
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Article
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2009
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American Society for Bone and Mineral Research
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English
โ 700 KB
Production of superoxide radicals by osteoclasts is necessary for normal bone degradation. White blood cell superoxide, needed for bacterial killing, is produced by activated NADPH oxidase. Since osteoclasts and white blood cells share a common hematopoietic origin, we initiated experiments to test