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Detection of Y-specific sequences in 122 patients with Turner syndrome: Nested PCR is not a reliable method

โœ Scribed by Nishi, Mirian Y. ;Domenice, Sorahia ;Medeiros, Maria Aparecida ;Mendonca, Berenice B. ;Billerbeck, Ana Elisa C.


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
103 KB
Volume
107
Category
Article
ISSN
0148-7299

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PCR detection of Y-specific sequences in
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Cytogenetic analysis of patients with Ullrich-Turner syndrome (UTS) may fail to detect low levels of Y chromosome mosaicism or Y-derived marker chromosomes. More sensitive polymerase chain reaction (PCR)-based tests have been developed; however, applicability of these data to prognosis of virilizati