Detection of various platelet-associated immunoglobulins by flow cytometry in idiopathic thrombocytopenic purpura
โ Scribed by Takuya Nishioka; Takahisa Yamane; Takayuki Takubo; Kensuke Ohta; Keunsik Park; Masayuki Hino
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 301 KB
- Volume
- 68B
- Category
- Article
- ISSN
- 1552-4949
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Platelet-associated IgG (PAIgG) was detected by means of anti-human IgG coated polyacrylamide beads ("Immunobeads") technique in 32 patients with chronic ITP. Both a direct test (with in vivo sensitized platelets) and an indirect test (with in vitro loaded platelets) were carried out. The percent of
The kinetics and distribution in vivo of 111In-labelled platelets prior to and during intravenous high-dose gamma globulin therapy in a 3-months-old child with idiopathic thrombocytopenic purpura were evaluated. Concomitantly with a prompt increase in platelet concentration we found evidence for rel