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Detection of Three Genetic Polymorphisms in the 5′-Flanking Region and Intron 1 of Human CYP1A2 in the Japanese Population

✍ Scribed by Chida, Michihiro ;Yokoi, Tsuyoshi ;Fukui, Takafumi ;Kinoshita, Moritoshi ;Yokota, Jun ;Kamataki, Tetsuya


Book ID
108581802
Publisher
Wiley (Blackwell Publishing)
Year
1999
Tongue
English
Weight
83 KB
Volume
90
Category
Article
ISSN
0910-5050

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The ATTTT repeat polymorphism located approximately 1,400 base pairs (bp) upstream from the beta-globin structural gene was analyzed by denaturing gradient gel electrophoresis (DGGE) of RNA:DNA duplexes. A study of 81 unrelated Japanese from Hiroshima revealed a sequence heteromorphism in this site.