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Detection of supercoiled hepatitis B virus DNA and related forms by means of molecular hybridization to an oligonucleotide probe

✍ Scribed by Dr. Hsiang Ju Lin; Hau Tim Chung; Ching Lung Lai; Susan Leong; Oi Sin Tam

Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
705 KB
Volume
29
Category
Article
ISSN
0146-6615

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A simple, direct molecular hybridization test was employed to detect hepatitis B virus (HBV) DNA sequences in human serum. In 61 HBsAg carriers, many with HBV-related diseases (chronic persistent hepatitis, chronic active hepatitis, or posthepatitic cirrhosis), 28/28 (100%) who were HBeAg+ and 16/32