The fragile histidine triad (FHIT) tumor suppressor gene at 3p14.2 has abnormalities in several types of human cancers. To investigate the potential role of FHIT in cervical cancer, which exhibits frequent loss of heterozygosity of 3p, we have examined primary cervical cancer samples from 28 patient
Detection of squamous cell carcinoma antigen in normal squamous epithelia and in squamous cell carcinomas of the uterine cervix
✍ Scribed by Gerd Crombach; Anton Scharl; Matthias Vierbuchen; Hannelore Würz; Achim Bolte
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 530 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## Objectives/Hypothesis: Previous studies have demonstrated a relationship between elevated serum squamous cell carcinoma (SCC) antigen (SCC‐Ag) levels and shorter survival in cancer patients. Few studies, however, have investigated the role of serum SCC‐Ag levels in oral SCC (OSCC).
The skillful help of Mrs. M. C. de Boer-Bisschops, Mrs. C. Kosterman-Claassen, Mr. R. Lodewijks, and Mrs. U. M. R. Vrij in performing the CEA assay, and of Mrs. A. Graafmans and Mrs. A. J. M. Pieterson-Scholts in collecting and handling the bloodsamples, is gratefully acknowledged.
A cell-mediated cytotoxicity assay was used to evaluate the specific reactivity of patients with squamous cell carcinoma to an established cell line derived from squamous cell carcinoma of the cervix. Heat inactivated sera from patients with squamous cell carcinoma could very effectively nullify thi