Use of fluorescent in situ hybridization
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Dr. Amato J. Giaccia; James W. Evans; J. Martin Brown
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Article
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1990
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John Wiley and Sons
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English
β 364 KB
In situ hybridization of hamsterlhuman hybrids with biotinylated human genomic D N A has revealed that human chromosomal DNA can integrate into the hamster genome and is not always cytologically detectable. This finding helps t o explain why discordancy can arise in gene mapping by failing to recogn