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Detection of serum DNA in cancer patients by modified methylation specific PCR

✍ Scribed by Yongchang Liu; Junning Sun; Xiaobo Liang; Qingjun Liu; Yuying Chen

Book ID
105634117
Publisher
Springer
Year
2002
Tongue
English
Weight
193 KB
Volume
1
Category
Article
ISSN
1610-1979

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## Abstract Methylation of CpG dinucleotides in the promoter sequence of a gene can lead to deregulated and suppressed gene expression. In this study, we have developed procedures for methylation‐specific polymerase chain reaction (MSP) and sequencing analysis to determine CpG methylation status of