Detection of poly(ADP-ribose) polymerase and its reaction product poly(ADP-ribose) by immunocytochemistry
✍ Scribed by Küpper, Jan-Heiner ;van Gool, Léon ;Müller, Marcus ;Bürkle, Alexander
- Publisher
- Springer
- Year
- 1996
- Tongue
- English
- Weight
- 617 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0018-2214
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## Background Poly(ADP-ribose) polymerase is evolutionarily conserved as a responder to various forms of stress. Though PARP's role in cell death is well addressed, its role in development and multicellularity is still an enigma. We have previously reported the role of PARP in oxidative stress indu
underestimated values for the AT duplexes (GC £ 50%, nucleotide oligos) Eq. [3] also gave similar satisfactory results (see Fig. ). AT § 50%). Deviations between predicted and experimental T m values are more scattered when Eqs. and The data presented here indicate that the thermal stability for s
## Abstract In previous studies we demonstrated that liver poly(ADP ribose) polymerase (pADPRP) activity was lost in animals exposed to __N__‐2‐acetylaminofluorene (2AAF) according to the Teebor and Becker experimental model (Cancer Res 31:1–3, 1971). In addition, we used the resistant hepatocyte m