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Detection of Poly(ADP-Ribose) Polymerase and Its Apoptosis-Specific Fragment by a Nonisotopic Activity–Western Blot Technique

✍ Scribed by Girish M. Shah; Scott H. Kaufmann; Guy G. Poirier


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
95 KB
Volume
232
Category
Article
ISSN
0003-2697

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✦ Synopsis


underestimated values for the AT duplexes (GC £ 50%, nucleotide oligos) Eq. [3] also gave similar satisfactory results (see Fig. ). AT § 50%). Deviations between predicted and experimental T m values are more scattered when Eqs. and

The data presented here indicate that the thermal stability for shorter oligonucleotides (£18) seems to be [2] are applied compared with Eq. [3] (Fig. ). Results also show that all three equations overestimated the independent of the GC content but is dependent on the length of the oligo. predicted T m values for oligonucleotide lengths higher than 20 nt (Fig. , A2 to C2).

Acknowledgments.