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Detection of p53 mutations via chemical cleavage of mismatches: fundamental aspects of the methodology and further perspectives

โœ Scribed by A.A. Neschastnova; A. Lambrinakos; V.K. Markina; O.A. Danilova; R.G.H. Cotton; G.A. Belitsky; M.G. Yakubovskaya


Book ID
117658273
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
170 KB
Volume
37
Category
Article
ISSN
0959-8049

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Novel TP53 gene mutations in tumors of R
โœ A. Lambrinakos; M. Yakubovskaya; J.J. Babon; A.A. Neschastnova; Ya.V. Vishnevska ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 281 KB ๐Ÿ‘ 2 views

## Communicated by Mark H. Paalman Mutations in the tumor-suppressor p53 gene TP53 are frequent in most human cancers including breast cancer. A new solid phase chemical cleavage of mismatch method (CCM) allowed rapid and efficient screening and analysis of the TP53 gene in DNA samples extracted