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403 POSTER Specificity and sensitivity of point mutation detection in tumor suppressor genes via chemical cleavage of mismatches

✍ Scribed by A.A. Belyakova; M.G. Yakubovskaya; V.K. Gasanova; G.A. Belitsky; N.G. Dolinnaya


Book ID
118625263
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
82 KB
Volume
5
Category
Article
ISSN
1359-6349

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## Communicated by Mark H. Paalman Mutations in the tumor-suppressor p53 gene TP53 are frequent in most human cancers including breast cancer. A new solid phase chemical cleavage of mismatch method (CCM) allowed rapid and efficient screening and analysis of the TP53 gene in DNA samples extracted