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Detection of NPM-ALK DNA rearrangement in CD30 positive anaplastic large cell lymphoma

โœ Scribed by W. Waggott; Y.-M. D. Lo; C. Bastard; K. C. Gatter; D. Leroux; D. Y. Mason; J. Boultwood; J. S. Wainscoat


Book ID
114714495
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
300 KB
Volume
89
Category
Article
ISSN
0007-1048

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Anaplastic large cell lymphoma (ALCL) comprises a group of non-Hodgkin lymphomas characterized by the expression of the CD30/Ki-1 antigen. A subset of ALCL is characterized by chromosomal translocations involving the anaplastic lymphoma kinase (ALK) gene on chromosome 2. While the most common transl