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Detection of minimal residual disease by PCR in childhood T-cell acute lymphoblastic leukemia with TAL1 gene rearrangement: A preliminary report

✍ Scribed by Kikuchi, Akira; Hanada, Ryoji; Yamamoto, Keiko; Hayashi, Yasuhide


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
63 KB
Volume
32
Category
Article
ISSN
0098-1532

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Deregulated expression of the TAL1 gene
✍ Sylvie FranΓ§ois; Eric Delabesse; Laurence Baranger; Marie Dautel; Charles Foussa πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 239 KB

TAL1 gene deregulation is frequent in T-cell acute lymphoblastic leukemia (T-ALL) and can result from translocations involving 1p32 or, more frequently, from a cytogenetically undetectable interstitial deletion of chromosome 1. This study presents a case of T-ALL with a t(1;5)(p32;q31) involving TAL