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Detection of methylated asparagine and glutamine residues in polypeptides

✍ Scribed by Alan V. Klotz; Beth Ann Thomas; Alexander N. Glazer; Russell W. Blacher

Book ID
102985146
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
647 KB
Volume
186
Category
Article
ISSN
0003-2697

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Mass spectrometric analysis of asparagin
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## Abstract One of the most frequent modifications in proteins and peptides is the deamidation of asparagine, a spontaneous non‐enzymatic reaction leading to a mixture of L,D‐succinimidyl, L,D‐aspartyl, and L,D‐isoaspartyl forms, with L‐isoaspartyl dominating. Spontaneous isomerization of L‐Asp yie