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Detection of methadone in human hair by gas chromatography/mass spectrometry

✍ Scribed by Balabanova, S. ;Arnold, P.J. ;Brunner, H. ;Luckow, V. ;Wolf, H.U.


Publisher
Springer-Verlag
Year
1989
Tongue
English
Weight
261 KB
Volume
102
Category
Article
ISSN
1437-1596

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✦ Synopsis


Determination of methadone in human hair by gas chromatography/ mass spectrometry was described. Helium as carrier gas, a 30-m bonded phasefused silica DB-1 capillary column and splitless injection at 230Β°C temperature were used. The concentrations of methadone and its metabolites were measured in addition by radioimmunoassay (RIA). Both methods GC/MS and RIA showed the presence of methadone in human hair. Key word: Methadone, in human hair Zusammenfassung. In dieser Arbeit wurde die Bestimmung von Methadon in menschlichen Haaren mittels Gaschromatographie/Massenspektrometrie (GC/MS) beschrieben. Als Tr~igergas wurde Helium benatzt; die S/iule war eine Kapillars/~ule DB-1 un die Injektion eine Splitlos-Injektion, bei einer Verdampfungstemperatur von 230Β°C. Die Methadonkonzentrationen in den Haaren wurden auch mittels Radioimmunoassay (RIA) durchgeftihrt. Beide Methoden GC/MS und RIA zeigen das Vorhandensein des Methadons im menschlichen Haar.


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