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Detection of IgA class antibody to hepatitis E virus in serum samples from patients with hepatitis E virus infection

✍ Scribed by Kurt H. Chau; George J. Dawson; Khalif M. Bile; Lars O. Magnius; Maria H. Sjogren; Isa K. Mushahwar


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
422 KB
Volume
40
Category
Article
ISSN
0146-6615

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✦ Synopsis


Abstract

A newly developed assay for IgA class antibody to hepatitis E virus (IgA anti‐HEV) was used to study 145 serum samples collected during an outbreak of an enterically transmitted hepatitis that occurred in 3 villages in the lower Shebeli region of Southern Somalia between January, 1988 and November, 1989. A total of 52.4% of the afflicted patients were found positive for IgA anti‐HEV, and 73.1% of these were also positive for IgM. Both antibodies disappeared during the convalescence period. Similar results were also seen in serum obtained from sporadic cases of acute waterborne hepatitis in Pakistan. Β© 1993 Wiley‐Liss, Inc.


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