✦ LIBER ✦

Detection of hepatitis a virus rna in serum from patients with acute hepatitis

✍ Scribed by R. Oren; D. Shouval; R. Tur-Kaspa

Publisher: John Wiley and Sons
Year: 1989
Tongue: English
Weight: 456 KB
Volume: 28
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890280411

No coin nor oath required. For personal study only.

✦ Synopsis

Hepatitis A virus (HAV) RNA was extracted from the sera of patients with acute hepatitis and then detected by molecular hybridization using cloned HAV complementary DNA (cDNA). HAV RNA was detected in 20 of 85 patients with acute HAV infection, mainly during the prodromal stage, or early during the icteric phase of the disease; it was detected as long as 21 days after its initial detection. Patients with HAV RNA in the serum had a significantly higher titer of anti-HAV IgM.

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