## Abstract Kaposi's sarcoma (KS) accounts for more than 15% of AIDSโrelated malignancies. The etiology of KS is unresolved but is postulated to be multiโfactorial, involving viruses and overexpression of cellular growth factors and/or oncogenes. Recently, herpesvirusโlike sequences (KSHV) were ide
Detection of herpesvirus-like DNA in HIV-associated and classical Kaposi's sarcoma
โ Scribed by Martin Simon; Peter Kind; Peter Kaudewitz; Armin Graf; Carl Georg Schirren; Mark Raffeld; Christian A. Sander
- Publisher
- Springer-Verlag
- Year
- 1996
- Tongue
- English
- Weight
- 573 KB
- Volume
- 288
- Category
- Article
- ISSN
- 0340-3696
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The identification of Kaposi's sarcoma (KS) clusters in subequatorial Africa (endemic KS, AKS) and the high frequency of KS in sexually transmitted AIDS (epidemic KS, EKS), have previously suggested a role for infectious agents in the etiopathogenesis of KS. The recent identification of herpesvirus
Kaposi's sarcoma (KS) is a malignancy suspected of having an infectious etiology. Unique viral DNA sequences were recognized in KS lesions, using a novel technique that identifies small differences between two complex genomes. The virus had homology with the herpesvirus family, especially Epstein Ba
## Abstract We report the molecular characterization of 38 new Kaposi's sarcomaโassociated herpesvirus (KSHV) strains from Russian patients with either classic (25 cases), epidemic/AIDSโassociated (7 cases), or posttransplant/immunosuppressed patients (6 cases), or Kaposi's sarcoma (KS). While a co