Detection of HER2/neu gene amplification in archival paraffin-embedded breast cancer tissues by fluorescence in situ hybridization
β Scribed by Sathiyamoorthy Selvarajan; Boon-Huat Bay; ShalawatiBinte Mamat; Andrew Choo; Khoon-Leong Chuah; ChristinaRudduck Sivaswaren; Sim-Leng Tien; Chow-Yin Wong; Puay-Hoon Tan
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 159 KB
- Volume
- 120
- Category
- Article
- ISSN
- 1432-119X
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Fluorescence in situ hybridization (FISH) is a validated method for detection of HER-2/neu gene amplification and was recently approved by the FDA for diagnostic use in paraffin-embedded tissue. Its use in cytologic specimens, however, has not been investigated. To see whether HER-2/neu gene amplifi
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