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Detection of gene deletions in Chinese patients with Duchenne/Becker muscular dystrophy using cDNA probes and the polymerase chain reaction method

✍ Scribed by Liu Yuge; Liu Hut; Xie Bingdi


Book ID
117176373
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
585 KB
Volume
65
Category
Article
ISSN
0024-3205

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Gene deletions were screened in 49 Japanese Duchenne muscular dystrophy patients from 43 families, using the polymerase chain reaction. Enzymatic amplification was carried out on six regions prone to deletion. Fifteen of 43 families (33%) had gene deletions in at least one of the six regions. This f