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A screening for dystrophin gene deletions in Japanese patients with Duchenne/Becker muscular dystrophy by the multiplex polymerase chain reaction

โœ Scribed by Sakuraba, Hitoshi; Ishii, Keiko; Shimmoto, Michie; Yamada, Hideo; Suzuki, Yoshiyuki


Book ID
123467876
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
447 KB
Volume
13
Category
Article
ISSN
0387-7604

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Screening of gene deletions by polymeras
โœ T. Nakajima; M. Matsuo; Y. Kitoh; T. Takumi; H. Nishio; T. Masumura; J. Koga; H. ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 399 KB

Gene deletions were screened in 49 Japanese Duchenne muscular dystrophy patients from 43 families, using the polymerase chain reaction. Enzymatic amplification was carried out on six regions prone to deletion. Fifteen of 43 families (33%) had gene deletions in at least one of the six regions. This f