Detection of gene copy number fluctuations with microarrays using genomic representations
โ Scribed by Lucito, Robert; Alexander, Joan; Rostan, Seth; West, Joseph; Wigler, Michael
- Book ID
- 109830461
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 27 KB
- Volume
- 27
- Category
- Article
- ISSN
- 1061-4036
- DOI
- 10.1038/87190
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## Communicated by Mireille Claustres Genomic imbalance is a major cause of developmental disorders. Microarray-based comparative genomic hybridization (aCGH) has revealed frequent imbalances associated with clinical syndromes, but also a large number of copy number variations (CNVs), which have co