Construction and use of spotted large-insert clone DNA microarrays for the detection of genomic copy number changes

Genomewide screening of DNA copy number

Genomewide screening of DNA copy number changes in chronic myelogenous leukemia with the use of high-resolution array-based comparative genomic hybridization

✍ Noriko Hosoya; Masashi Sanada; Yasuhito Nannya; Kumi Nakazaki; Lili Wang; Akira 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 251 KB

## Abstract Chronic myelogenous leukemia (CML) evolves from an indolent chronic phase (CP) characterized by the Philadelphia chromosome. Without effective therapy, it progresses to an accelerated phase (AP) and eventually to a fatal blast crisis (BC). To identify the genes involved in stage progres