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Detection of cytomegalovirus antigen and antibodies in the urine of small infants and children

✍ Scribed by Shehla H. Naqvi; Laura L. Blair

Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
532 KB
Volume
18
Category
Article
ISSN
0146-6615

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✦ Synopsis

The diagnostic efficacy of an enzyme immune assay to detect cytomegalovirus (CMV) antigen in the urine of infected infants and children was determined, and the effect that CMV-specific antibodies present in the urine have on the sensitivity of the test was ascertained. The antigen was detected in 84.4% of the CMV-culture-positive samples, while CMV-specific IgA was detected in 24% of CMV-culture-positive specimens. The absence of CMV-specific IgA correlated with detection of CMV antigen in the CMV-culture-positive urine specimens (p less than 0.05).

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