Antibodies to epidermal-growth-factor receptor (EGF) and transforming growth factor-a (TGVa) were used to determine the role of endogenous TGF-a in the growth of 2 human colon-carcinoma cell lines. Both the GEO and HCT I 16 coloncarcinoma cell lines secrete similar levels of TGF-a and have similar n
Detection of colonic growth factors using a human colonic carcinoma cell line (LIM 1215)
β Scribed by R. H. Whitehead; E. C. Nice; C. J. Lloyd; R. James; A. W. Burgess
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- French
- Weight
- 625 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
β¦ Synopsis
Concentration of mitogen (nglml) which stimulated 50% maximal thymidine incorporation.-2Maximum stimulation by IL-1 was only 50% of the stimulation achieved with EGF.-3NR, not responsive (highest concentration tested in the assay). -4See detailed results in Figure 2.-5Maximum stimulation by IGF-I was only 20% of the stimulation achieved with EGF.
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