𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Detection of colonic growth factors using a human colonic carcinoma cell line (LIM 1215)

✍ Scribed by R. H. Whitehead; E. C. Nice; C. J. Lloyd; R. James; A. W. Burgess


Publisher
John Wiley and Sons
Year
1990
Tongue
French
Weight
625 KB
Volume
46
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis


Concentration of mitogen (nglml) which stimulated 50% maximal thymidine incorporation.-2Maximum stimulation by IL-1 was only 50% of the stimulation achieved with EGF.-3NR, not responsive (highest concentration tested in the assay). -4See detailed results in Figure 2.-5Maximum stimulation by IGF-I was only 20% of the stimulation achieved with EGF.


πŸ“œ SIMILAR VOLUMES


Differential role of transforming growth
✍ Linda F. Watkins; Alan E. Levine πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 French βš– 702 KB

Antibodies to epidermal-growth-factor receptor (EGF) and transforming growth factor-a (TGVa) were used to determine the role of endogenous TGF-a in the growth of 2 human colon-carcinoma cell lines. Both the GEO and HCT I 16 coloncarcinoma cell lines secrete similar levels of TGF-a and have similar n

Epidermal growth factor expression in hu
✍ Sriram Rajagopal; Shuang Huang; Thomas L. Moskal; Bang-Ning Lee; Adel K. El-Nagg πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 French βš– 961 KB

## Abstract Human colon cancer cell lines express epidermal growth factor (EGF) mRNA, secrete EGF and may respond to it __via__ the cell‐surface EGF receptor (EGFR). Expression of these molecules in human colon and colon tumor, however, is not clear. Reverse transcription‐polymerase chain reaction

Amphiregulin anti-sense oligodeoxynucleo
✍ Nicola Normanno; Mouna P. Selvam; Caterina Bianco; Vincenzo Damiano; Ernesto de πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 French βš– 604 KB

Amphiregulin (AR) is a secreted heparin-binding growth factor that is structurally and functionally related to epidermal growth factor (EGF) and transforming growth factor a (TGFa). CEO cells are from a human colon cancer cell line that expresses high levels of AR protein and mRNA. To assess the rol

Increased transforming growth factor-Ξ± l
✍ Padma Maruvada; Alan E. Levine πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 French βš– 154 KB πŸ‘ 1 views

Transforming growth factor-␣ (TGF-␣) is synthesized as a membrane-bound precursor protein, pro-TGF-␣, that is converted to a soluble form by 2 endoproteolytic cleavages. Several factors have been implicated in the regulation of the second rate-limiting step, including protein kinase C (PKC). Earlier